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Research

NACC Research Reports

NACC sometimes commissions research or reviews into particular aspects of Inflammatory Bowel Diseases, both into research and service development issues. You can read the reports by following this link. If you wish to quote from the reports please provide people with a reference to the full reports here on the NACC website.

NACC Research Fund

More than 100 projects have been funded by NACC members since the Research Fund was started in 1984. The research has been mainly into the causes and treatments for Inflammatory Bowel Disease, but in recent years several Social and Psychological projects have been funded. The funds for research have come almost entirely from NACC members own fund-raising and donations, but support from Charitable Trusts and Companies is growing. Our aim is to increase the funds we make available to £500,000 per year by the end of 2007.

If you would like to make a donation to the Research Fund, please click here; if you would like to discuss fundraising for the NACC research Fund, please email .

NACC's policy has been to fund projects at hospitals and universities throughout the United Kingdom, not just at one centre. Awards are made using peer-review and the projects funded have covered a wide variety of possible causes, including genetics, viruses and bacteria, the immune system and the environment. No single line of research seems to offer a complete understanding of the disease and NACC aims to help research progress in all areas. NACC has been awarded a Certificate of Best Practice in peer-review of research applications by the Association of Medical Research Charities (AMRC).

Summary of Research Awards 1984 to 2006

NACC has produced a summary of NACC research from 2001 to 2006 which can be downloaded in PDF format (880kb - this is a large file which will take about 4 minutes to download on a standard 56k modem).  An earlier review covering NACC research from 1984 to 2001 can also be downloaded in PDF format (1.2mb - this is a large file which will take about 6 minutes to download on a standard 56k modem).

List of Research Awards

Research Awards since 2005 are listed here in reverse date order (latest year first) sorted by the size of the grant. The total for each year is shown at the end of that year's listings; older awards since 2000 are also available.

Research Awards - Applying to NACC

To apply for a NACC Research award, please click here.

2008

Professor Christopher Probert - Clinical Science South Bristol, Bristol Royal Infirmary
Steroid Resistant Lymphocyte Populations in Ulcerative Colitis
£100,000 (2 years)
Paragraph marker bulletClick here for the lay summary           


Dr Barry Campbell - University of Liverpool, Division of Gastroenterology
Identifying the molecular mechanisms of interaction between colonic Crohn's disease mucosa-associated Escherichia coli and the intestinal epithelium
£89,341 (2 years)
Paragraph marker bulletClick here for the lay summary           


Professor George MacFarlane - Gut Group, Division of Pathology and Neuroscience
Synbiotic treatment of ulcerative colitis patients
£86,950 (2 years)
Paragraph marker bulletClick here for the lay summary           


Dr David Qualtrough - Department of Cellular & Molecular Medicine, University of Bristol
The role of Notch signalling in restitution, regeneration and remission in inflammatory bowel disease
£7,791 (1 year)
Paragraph marker bulletClick here for the lay summary           


Research Awards for 2008 totalled: £284,082  

2007

Professor David Rampton - Endoscopy Unit, Royal London Hospital
How does Psychological Stress Exacerbate Ulcerative Colitis? Roles of mucosa-associated bacteria, mast cells and catecholamines
£85,000 (2 years)
Paragraph marker bulletClick here for the lay summary           


Dr Christine Whiting - School of Clinical Veterinary Science, University of Bristol
IL-13 promotes inflammation-induced gut fibrosis via a TNF-?-dependent mechanism
£67,106 (1 year)
Paragraph marker bulletClick here for the lay summary           


Dr Jeremy Sanderson - School of Biomedical and Health Sciences, Kings College London
The difficult problem of oral Crohn’s disease: a unique pathological entity in IBD?
£51,975 (1 year)
Paragraph marker bulletClick here for the lay summary           


Dr Louise Langmead - Department of Gastroenterology UCLH
Clinical trial to evaluate aloe vera gel enemas in mild to moderately active distal ulcerative colitis (UC)
£30,127 (1 year)
Paragraph marker bulletClick here for the lay summary           


Dr Jeremy Sanderson - School of Biomedical and Health Sciences, Kings College London
Optimising thiopurine metabolite monitoring to allow personalised thiopurine treatment
£9,300 (1 year)
Paragraph marker bulletClick here for the lay summary           


Research Awards for 2007 totalled: £243,508  

2006

Prof Subrata Ghosh - Imperial College London
Control of adaptive immune responses via Crohn’s disease-associated NOD2 signalling and bacterial sensing in human dentritic cells
£95,242 (2 years)
Paragraph marker bulletClick here for the lay summary           


Dr Amanda Williams - University of Bristol
Is selection pressure responsible for chronic refractory IBD? – Does initial steroid therapy ultimately lead to treatment failure by preferential selection of disease-propagating T cells?
£89,987 (2 years)
Paragraph marker bulletClick here for the lay summary           


Dr Andrew Smith - University College London
Macrophages from Crohn’s disease patients have an impaired response to inflammatory stimuli
£20,000 (1 year)
Paragraph marker bulletClick here for the lay summary           


Dr Gordon Dent - Keele University
Eosinophil/epithelium interactions in inflammatory bowel disease: a pilot study
£3,000 (1 year)
Paragraph marker bulletClick here for the lay summary           


Research Awards for 2006 totalled: £208,229  

Quick Links on this page:

-Previous page

-NACC Research Reports

-Research Awards - Applying to NACC

-Research Awards Archive

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